Viruses (Oct 2010)

Towards Viral Genome Annotation Standards, Report from the 2010 NCBI Annotation Workshop

  • Qiandong Zeng,
  • William Klimke,
  • Peter Sterk,
  • Susmita Shrivastava,
  • Ramana Madupu,
  • Richard H. Scheuermann,
  • Seth Schobel,
  • Donald Seto,
  • Yiming Bao,
  • Carla Kuiken,
  • Elliot J. Lefkowitz,
  • Philippe Le Mercier,
  • Raphael Leplae,
  • Tatiana Tatusova,
  • James Rodney Brister

DOI
https://doi.org/10.3390/v2102258
Journal volume & issue
Vol. 2, no. 10
pp. 2258 – 2268

Abstract

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Improvements in DNA sequencing technologies portend a new era in virology and could possibly lead to a giant leap in our understanding of viral evolution and ecology. Yet, as viral genome sequences begin to fill the world’s biological databases, it is critically important to recognize that the scientific promise of this era is dependent on consistent and comprehensive genome annotation. With this in mind, the NCBI Genome Annotation Workshop recently hosted a study group tasked with developing sequence, function, and metadata annotation standards for viral genomes. This report describes the issues involved in viral genome annotation and reviews policy recommendations presented at the NCBI Annotation Workshop.

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