Indonesian Journal of Chemistry (Jul 2010)

6,6’-DIMETHOXY-4,4’-DIHYDROXY-3’,2’-FURANO-ISOFLAVANE, A NEW COMPOUND FROM <i>Melochia umbellata</i> (Houtt.) Stapf <i>var.</i> Degrabrata K. (<i>Paliasa</i>)

  • Erwin Erwin,
  • Alfian Noor,
  • Nunuk Hariani Soekamto,
  • Tjodi Harlim

DOI
https://doi.org/10.22146/ijc.21463
Journal volume & issue
Vol. 10, no. 2
pp. 215 – 218

Abstract

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Using data from UV, IR, 1H-NMR, 13C-NMR, dan NMR-2D analysis, a compound of 6,6'-dimethoxy-4,4'-dihydroxy-3',2'-furano-isoflavane (1) was successfully isolated from chloroform fraction of heartwood in Melochia umbellata (Houtt.) Stapf var. Degrabarata K (Paliasa). Hitherto no report of such compound found in literature. The compound however has not shown a significant bioactivity according to either brine shrimp lethality test or evaluation of anti tumor activity against leukemia murine cell (P-388). Keywords: isoflavane, heartwood, chloroform and Melochia umbellata