A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans

Yunjiang Yu; Haibo Chen; Xin Hua; Chen Wang; Chenyin Dong; Dongli Xie; Shihui Tan; Mingdeng Xiang; Hui Li

Hygiene and Environmental Health Advances (Sep 2022)

A review of the reproductive toxicity of environmental contaminants in Caenorhabditis elegans

Yunjiang Yu,
Haibo Chen,
Xin Hua,
Chen Wang,
Chenyin Dong,
Dongli Xie,
Shihui Tan,
Mingdeng Xiang,
Hui Li

Affiliations

Yunjiang Yu: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; Corresponding authors.
Haibo Chen: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR China
Xin Hua: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China
Chen Wang: Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR China
Chenyin Dong: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China
Dongli Xie: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; College of Environmental and Chemical Engineering, Chongqing Three Gorges University, Wanzhou 404100, PR China
Shihui Tan: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China; School of Public Health, China Medical University, Liaoning 110122, PR China
Mingdeng Xiang: State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510655, PR China
Hui Li: Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, PR China; Corresponding authors.

Journal volume & issue: Vol. 3
p. 100007

Abstract

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The release of several environmental pollutants poses a potential threat to the several ecosystems and humans. Reproductive toxicity represents one of the most significant toxic effects of environmental contaminants. It is necessary to assess reproductive toxicity and the mechanisms underlying environmental toxicity in organisms. Because of its unique features in toxicology research, Caenorhabditis elegans is an important animal model used for the toxicity assessment of environmental contaminants. In this review, we introduce the reproductive toxicity and mechanisms underlying the actions of environmental contaminants, including heavy metals, organic pollutants, particulate matter, microplastics, nanomaterials, and irradiation. Moreover, we have put forth some perspectives about toxicity assessments, transgenerational toxicity, and toxicological mechanisms of environmental contaminants in the future.

Published in Hygiene and Environmental Health Advances

ISSN: 2773-0492 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Public aspects of medicine; Geography. Anthropology. Recreation: Environmental sciences
Website: https://www.sciencedirect.com/journal/hygiene-and-environmental-health-advances

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