Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation

Yasuhiro Ebihara; Shohei Yamamoto; Shinji Mochizuki; Masao Tsukada; Yuki Taya; Toshiro Kawakita; Seiko Kato; Jun Ooi; Satoshi Takahashi; Arinobu Tojo; Kohichiro Tsuji

doi:10.4081/hr.2013.e10

Hematology Reports (Jun 2013)

Pneumothorax in an early phase after allogeneic hematopoietic stem cell transplantation

Yasuhiro Ebihara,
Shohei Yamamoto,
Shinji Mochizuki,
Masao Tsukada,
Yuki Taya,
Toshiro Kawakita,
Seiko Kato,
Jun Ooi,
Satoshi Takahashi,
Arinobu Tojo,
Kohichiro Tsuji

Affiliations

Yasuhiro Ebihara: Department of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Shohei Yamamoto: Department of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Shinji Mochizuki: Division of Stem Cell Processing, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo
Masao Tsukada: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Yuki Taya: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Toshiro Kawakita: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Seiko Kato: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Jun Ooi: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Satoshi Takahashi: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Arinobu Tojo: Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo
Kohichiro Tsuji: Department of Pediatric Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo; Division of Stem Cell Processing, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo; Department of Pediatrics, Shinshu Ueda Medical Center

DOI: https://doi.org/10.4081/hr.2013.e10
Journal volume & issue: Vol. 5, no. 2
pp. e10 – e10

Abstract

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Pneumothorax is very rare after early phase of hematopoietic stem cell transplantation (HSCT) and usually accompanied with pulmonary chronic graft-versus-host disease (GVHD), such as bronchiolitis obliterans and bronchiolitis obliterans organizing pneumonia. The present study describes the case of a seventeen-year-old male diagnosed with acute myeloid leukemia who underwent allogeneic bone marrow transplantation (BMT). Pneumothorax occurred at day 43 after BMT. Pneumothorax occurred in early phase of HSCT is extremely rare. The early onset of acute GVHD and the entity of cytomegalovirus might worsen the pulmonary tissue damages for the onset of pneumothorax, indicating that we should be aware of the possibility to occur pneumothorax even in the early period after allogeneic HSCT.

pneumothorax, air-leak syndrome, allogeneic hematopoietic stem cell transplantation

Published in Hematology Reports

ISSN: 2038-8330 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the blood and blood-forming organs
Website: https://www.mdpi.com/journal/hematolrep

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