Etiologic and Clinical Features of Cerebral Venous Sinus Thrombosis in Saudi Arabia

Journal of Neurosciences in Rural Practice. 2019;10(02):278-282 DOI 10.4103/jnrp.jnrp_305_18

 

Journal Homepage

Journal Title: Journal of Neurosciences in Rural Practice

ISSN: 0976-3147 (Print); 0976-3155 (Online)

Publisher: Thieme Medical and Scientific Publishers Pvt. Ltd.

Society/Institution: Associacion Ayuda Enfermo Neuroquirurgico (Association for Helping Neurosurgical Sick People)

LCC Subject Category: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry

Country of publisher: United States

Language of fulltext: English

Full-text formats available: PDF, HTML, ePUB

 

AUTHORS


Rizwana Shahid (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Azra Zafar (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Saima Nazish (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Abdulla Alsulaiman (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Majed Alabdali (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Danah Aljaafari (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Noman Ishaque (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Aishah Ibrahim Albakr (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Abdullah Alamri (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Fahd A. Alkhamis (Department of Neurology, King Fahd Hospital of University Alkhobar, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia)

Maher Saqqur (Department of Medicine, Division of Neurology, 7-112L Clinical Sciences Building, University of Alberta, Edmonton, Canada)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 22 weeks

 

Abstract | Full Text

Objective: Our study aims to evaluate the etiologic and clinical features of cerebral venous sinus thrombosis (CVST) in Saudi Arabia, and secondarily whether gender plays a role in CVST. Materials and Methods: Data were collected retrospectively from the stroke registry during the period from January 2008 to April 2018, and the patients with the diagnosis of CVST were identified, and data were analyzed for any gender-specific differences in clinical presentation and etiology of cerebral venous thrombosis. Results: There were 15 females while 11 males with a female:male ratio of 1.4:1. The mean age was 29.4± standard deviation 8.9 with the age range of 15–49. Headache was the most common and usually the first presenting symptoms present in 65% followed by hemiparesis and cranial nerve palsies. The first neurological examination was normal in 9/26 (34.6%) of the patients, while the common abnormality was cranial nerve palsies. Infections and trauma played an important part in risk factor analysis of our patient after the pregnancy- and hormone-related conditions. Some significant differences between the clinical presentation and risk factors among males and females were noted as age at presentation was higher in females while trauma and infections were common in male patients, although the involvement of the sinuses and response to treatment did not prove to be statistically significant. Conclusion: The results of this study were similar to the available literature with few differences. The relatively higher proportion of males in our study can be explained partly with more cases of traumatic CVST. Some important differences were noted between the risk factors and clinical presentation among genders. Large-scale prospective studies are needed to further clarify these differences.