Hyperuricemia as a risk factor for arterial hypertension among the population of the Fergana region of the Republic of Uzbekistan

Abstract

Today, a lot of data has been accumulated on the role of purine metabolism disorders in the development of a number of diseases, including cardiovascular diseases. However, the results of a large number of epidemiological and clinical studies aimed at detecting the pathogenetic relationship between hyperuricemia (HU) and arterial hypertension (AH) are contradictory. According to the purpose of the study - to study the epidemiological conditions in relation to hypertension in connection with HU and other risk factors in order to be ¬able to plan multifactorial prevention on this basis, we carried out epidemiological study ¬of hypertension due to a combination of risk factors such as HU, impaired carbohydrate tolerance (IHT), pesticideemia, dyslipoproteinemia (DLP), overweight and smoking among rural men ¬and women of working age. We chose a continuous method of epidemiological examination with the measurement of blood pressure, ECG, anthropometric and biochemical studies. To determine the groups for primary, secondary and tertiary prevention, we have established the level of individual risk of developing hypertension. On this basis, a percentile distribution was built and the entire population of men and women was divided into 3 groups: 1-group of moderate risk (84.6%); 2-high-risk group (10.3%) and 3-group of patients (5.1%).