National Journal of Laboratory Medicine (Jul 2013)
Rosai-Dorfman Disease- A Surprise diagnosis in Follow up of SCC Pyriform Sinus -Post Surgery and CTRT
Abstract
Rosai-Dorfman disease also known as Sinus Histiocytosis with massive Lymphadenopathy (SHML). SHML was first described by Rosai and Dorfman in 1969 [1] and is now considered a non malignant inflammatory disorder in which the precise origin of pathologic cells is still controversial [2]. SHML is a rare self-limited pseudolymphomatous disorder of unknown etiology usually present with cervical lymphadenopathy, fever, elevated ESR and hematological abnormalities [3].There is a higher prevalence in males, and among Afro-Caribbeans as compared to Caucasians and Asians. Also, a familial association has been observed in some cases [4]. We present a case of 60-year-old male patient with a case of RosaiDorfman Disease in Follow up of SCC Pyriform Sinus-Post Surgery and CTRT
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