Journal of Clinical Medicine (Mar 2023)

Elective Ascending Aortic Aneurysm Surgery in the Elderly

  • Feyza Memis,
  • Carlijn G. E. Thijssen,
  • Arjen L. Gökalp,
  • Maximiliaan L. Notenboom,
  • Frederike Meccanici,
  • Mohammad Mostafa Mokhles,
  • Roland R. J. van Kimmenade,
  • Kevin M. Veen,
  • Guillaume S. C. Geuzebroek,
  • Jelena Sjatskig,
  • Franciscus J. ter Woorst,
  • Jos A. Bekkers,
  • Johanna J. M. Takkenberg,
  • Jolien W. Roos-Hesselink

DOI
https://doi.org/10.3390/jcm12052015
Journal volume & issue
Vol. 12, no. 5
p. 2015

Abstract

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Background. No clear guidelines exist for performing preventive surgery for ascending aortic (AA) aneurysm in elderly patients. This study aims to provide insights by: (1) evaluating patient and procedural characteristics and (2) comparing early outcomes and long-term mortality after surgery between elderly and non-elderly patients. Methods. A multicenter retrospective observational cohort-study was performed. Data was collected on patients who underwent elective AA surgery in three institutions (2006–2017). Clinical presentation, outcomes, and mortality were compared between elderly (≥70 years) and non-elderly patients. Results. In total, 724 non-elderly and 231 elderly patients were operated upon. Elderly patients had larger aortic diameters (57.0 mm (IQR 53–63) vs. 53.0 mm (IQR 49–58), p p p = 0.16). Five-year survival was 93.9% in non-elderly patients and 81.4% in elderly patients (p < 0.001), which are both lower than that of the age-matched general Dutch population. Conclusion. This study showed that in elderly patients, a higher threshold exists to undergo surgery, especially in elderly females. Despite these differences, short-term outcomes were comparable between ‘relatively healthy’ elderly and non-elderly patients.

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