Journal of Extracellular Vesicles (Dec 2017)
A novel community driven software for functional enrichment analysis of extracellular vesicles data
- Mohashin Pathan,
- Shivakumar Keerthikumar,
- David Chisanga,
- Riccardo Alessandro,
- Ching-Seng Ang,
- Philip Askenase,
- Arsen O. Batagov,
- Alberto Benito-Martin,
- Giovanni Camussi,
- Aled Clayton,
- Federica Collino,
- Dolores Di Vizio,
- Juan Manuel Falcon-Perez,
- Pedro Fonseca,
- Pamali Fonseka,
- Simona Fontana,
- Yong Song Gho,
- An Hendrix,
- Esther Nolte-’t Hoen,
- Nunzio Iraci,
- Kenneth Kastaniegaard,
- Thomas Kislinger,
- Joanna Kowal,
- Igor V. Kurochkin,
- Tommaso Leonardi,
- Yaxuan Liang,
- Alicia Llorente,
- Taral R. Lunavat,
- Sayantan Maji,
- Francesca Monteleone,
- Anders Øverbye,
- Theocharis Panaretakis,
- Tushar Patel,
- Héctor Peinado,
- Stefano Pluchino,
- Simona Principe,
- Goran Ronquist,
- Felix Royo,
- Susmita Sahoo,
- Cristiana Spinelli,
- Allan Stensballe,
- Clotilde Théry,
- Martijn J.C. van Herwijnen,
- Marca Wauben,
- Joanne L. Welton,
- Kening Zhao,
- Suresh Mathivanan
Affiliations
- Mohashin Pathan
- La Trobe University
- Shivakumar Keerthikumar
- La Trobe University
- David Chisanga
- La Trobe University
- Riccardo Alessandro
- University of Palermo
- Ching-Seng Ang
- The University of Melbourne
- Philip Askenase
- Yale University School of Medicine
- Arsen O. Batagov
- A*STAR
- Alberto Benito-Martin
- Weill Cornell Medical College
- Giovanni Camussi
- University of Torino, Medical School
- Aled Clayton
- Cardiff University, Velindre Cancer Centre
- Federica Collino
- University of Torino, Medical School
- Dolores Di Vizio
- Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Juan Manuel Falcon-Perez
- Bikaia and IKERBASQUE Research Foundation
- Pedro Fonseca
- Karolinska Institutet and Karolinska University Hospital Solna
- Pamali Fonseka
- La Trobe University
- Simona Fontana
- University of Palermo
- Yong Song Gho
- Pohang University of Science and Technology
- An Hendrix
- Ghent University
- Esther Nolte-’t Hoen
- Utrecht University
- Nunzio Iraci
- University of Catania
- Kenneth Kastaniegaard
- Aalborg University
- Thomas Kislinger
- Princess Margaret Cancer Centre
- Joanna Kowal
- PSL Research University, INSERM U932
- Igor V. Kurochkin
- A*STAR
- Tommaso Leonardi
- University of Cambridge
- Yaxuan Liang
- Icahn School of Medicine at Mount Sinai
- Alicia Llorente
- Oslo University Hospital-The Norwegian Radium Hospital
- Taral R. Lunavat
- University of Gothenburg
- Sayantan Maji
- Mayo Clinic
- Francesca Monteleone
- University of Palermo
- Anders Øverbye
- Oslo University Hospital-The Norwegian Radium Hospital
- Theocharis Panaretakis
- Karolinska Institutet and Karolinska University Hospital Solna
- Tushar Patel
- Mayo Clinic
- Héctor Peinado
- Weill Cornell Medical College
- Stefano Pluchino
- University of Cambridge
- Simona Principe
- Princess Margaret Cancer Centre
- Goran Ronquist
- Uppsala University
- Felix Royo
- Bikaia and IKERBASQUE Research Foundation
- Susmita Sahoo
- Icahn School of Medicine at Mount Sinai
- Cristiana Spinelli
- Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Allan Stensballe
- Aalborg University
- Clotilde Théry
- PSL Research University, INSERM U932
- Martijn J.C. van Herwijnen
- Utrecht University
- Marca Wauben
- Utrecht University
- Joanne L. Welton
- Cardiff Metropolitan University
- Kening Zhao
- La Trobe University
- Suresh Mathivanan
- La Trobe University
- DOI
- https://doi.org/10.1080/20013078.2017.1321455
- Journal volume & issue
-
Vol. 6,
no. 1
Abstract
Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture “what the community needs in a tool”. Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.
Keywords
