Association between Rutherford Classification and CHA2DS2-VASc, CHADS2 and ASCVD Scores in Peripheral Artery Disease Patients

Abstract

Background and Aim: The classification system is important in assessing the severity of Peripheral Artery Disease (PAD) and making the treatment decision. However, classification systems may not be sufficient and scoring systems developed to predict cardiovascular and cerebrovascular events can also be useful to assess the severity of PAD. In this study, our aim was to investigate the association of the Rutherford classification and CHADS2, CHA2DS2-VASc and ASCVD scores in PAD patients. Method: A total of 65 consecutive patients with PAD (males 92.3%, mean age 63.0 ± 9.2 years), who underwent percutaneous peripheral intervention were included in our retrospective study. Results: There were 16 patients in Category 2, 31 patients in Category 3, and 10 patients in Category 4 and eight patients in Category 5. The CHADS2, CHA2DS2-VASc and ASCVD scores were found to be significantly different among the Rutherford categories and between each other. From Category 1 to 5, CHADS2, CHA2DS2-VASc and ASCVD scores were significantly increased. When we grouped the scores as CHADS2 <2 and ≥2 and CHA2DS2-VASc <4 and ≥4, it was determined that as the category increased the score group also increased. There was significantly correlation between CHADS2, CHA2DS2-VASc and ASCVD scores with the Rutherford categories in correlation analyses. Conclusion: As far as we know, in this study which is the first study about the association of Rutherford classification and scoring systems, the major finding of the present study is that the CHADS2, CHA2DS2-VASc and ASCVD scores was independently correlated with the severity of Rutherford Category in patients with PAD.

Keywords

• Peripheral artery disease
• Rutherford classification
• CHADS2
• CHA2DS2-VASc
• ASCVD