Environment International (Nov 2018)
Residential air pollution does not modify the positive association between physical activity and lung function in current smokers in the ECRHS study
- Elaine Fuertes,
- Iana Markevych,
- Deborah Jarvis,
- Danielle Vienneau,
- Kees de Hoogh,
- Josep Maria Antó,
- Gayan Bowatte,
- Roberto Bono,
- Angelo G. Corsico,
- Margareta Emtner,
- Thorarinn Gislason,
- José Antonio Gullón,
- Joachim Heinrich,
- John Henderson,
- Mathias Holm,
- Ane Johannessen,
- Bénédicte Leynaert,
- Alessandro Marcon,
- Pierpaolo Marchetti,
- Jesús Martínez Moratalla,
- Silvia Pascual,
- Nicole Probst-Hensch,
- José Luis Sánchez-Ramos,
- Valerie Siroux,
- Johan Sommar,
- Joost Weyler,
- Nino Kuenzli,
- Bénédicte Jacquemin,
- Judith Garcia-Aymerich
Affiliations
- Elaine Fuertes
- ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; Population Health and Occupational Diseases, National Heart and Lung Institute, Imperial College London, London, United Kingdom; Corresponding author at: Doctor Aiguader, 88, E-08003 Barcelona, Spain
- Iana Markevych
- Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Germany; Helmholtz Zentrum München - German Research Center for Environmental Health, Institute of Epidemiology I, Neuherberg, Germany
- Deborah Jarvis
- Population Health and Occupational Diseases, National Heart and Lung Institute, Imperial College London, London, United Kingdom; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom
- Danielle Vienneau
- Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland
- Kees de Hoogh
- Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland
- Josep Maria Antó
- ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
- Gayan Bowatte
- Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, School of Population and Global Health, The University of Melbourne, Melbourne, Australia
- Roberto Bono
- Department of Public Health and Pediatrics, University of Turin, Turin, Italy
- Angelo G. Corsico
- Division of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
- Margareta Emtner
- Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden
- Thorarinn Gislason
- Department of Respiratory Medicine and Sleep, Landspitali University Hospital Reykjavik, Reykjavik, Iceland
- José Antonio Gullón
- Department of Pneumology, Hospital San Agustín, Avilés, Asturias, Spain
- Joachim Heinrich
- Population Health and Occupational Diseases, National Heart and Lung Institute, Imperial College London, London, United Kingdom; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Germany
- John Henderson
- Population Health Sciences, Britsol Medical School, University of Bristol, Bristol, United Kingdom
- Mathias Holm
- Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
- Ane Johannessen
- Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway; Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway
- Bénédicte Leynaert
- Inserm, UMR 1152, Pathophysiology and Epidemiology of Respiratory Diseases, Paris, France; University Paris Diderot Paris, UMR 1152, Paris, France
- Alessandro Marcon
- Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy
- Pierpaolo Marchetti
- Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy
- Jesús Martínez Moratalla
- Servicio de Neumología del Complejo Hospitalario Universitario de Albacete, (CHUA), Albacete, Spain; Servicio de Salud de Castilla – La Mancha (SESCAM), Spain; Facultad de Medicina de Albacete, Universidad de Castilla - La Mancha, Albacete, Spain
- Silvia Pascual
- Respiratory Department, Galdakao Hospital, OSI Barrualde-Galdakao, Biscay, Spain
- Nicole Probst-Hensch
- Swiss Tropical and Public Health Institute, Basel, Switzerland; Department Public Health, University of Basel, Basel, Switzerland
- José Luis Sánchez-Ramos
- Department of Nursing, University of Huelva, Huelva, Spain
- Valerie Siroux
- Institute for Advanced Biosciences, UGA-Inserm U1209-CNRS UMR 5309, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, Grenoble, France
- Johan Sommar
- Occupational and Environmental Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
- Joost Weyler
- Epidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium
- Nino Kuenzli
- Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland
- Bénédicte Jacquemin
- ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; VIMA: Aging and Chronic Diseases, Epidemiological and Public Health Approaches, U1168, Institut Médical de Santé et Recherche Médicale, Villejuif, France; Unité mixte de recherche (UMR)-S1168, Université Versailles St-Quentin-en-Yvelines, Versailles, France
- Judith Garcia-Aymerich
- ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
- Journal volume & issue
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Vol. 120
pp. 364 – 372
Abstract
Background: Very few studies have examined whether a long-term beneficial effect of physical activity on lung function can be influenced by living in polluted urban areas. Objective: We assessed whether annual average residential concentrations of nitrogen dioxide (NO2) and particulate matter with aerodynamic diameters 75th percentile (high)). Results: Among current smokers, physical activity and lung function were positively associated regardless of air pollution levels. Among never-smokers, physical activity was associated with lung function in areas with low/medium NO2, PM2.5 mass and PM10 mass concentrations (e.g. mean difference in FVC between active and non-active subjects was 43.0 mL (13.6, 72.5), 49.5 mL (20.1, 78.8) and 49.7 mL (18.6, 80.7), respectively), but these associations were attenuated in high air pollution areas. Only the interaction term of physical activity and PM10 mass for FEV1 among never-smokers was significant (p-value = 0.03). Conclusions: Physical activity has beneficial effects on adult lung function in current smokers, irrespective of residential air pollution levels in Western Europe. Trends among never-smokers living in high air pollution areas are less clear. Keywords: Air pollution, Cohort, Lung function, Physical activity, Smoking
