Diagnostic Pathology (Nov 2012)

Postoperative lumbar spinal stenosis after intertransverse fusion with granules of hydroxyapatite: a case report

  • Inoue Gen,
  • Ohtori Seiji,
  • Ozawa Tomoyuki,
  • Ito Toshinori,
  • Higashi Morihiro,
  • Yamauchi Kazuyo,
  • Orita Sumihisa,
  • Nakamura Junichi,
  • Toyone Tomoaki,
  • Takaso Masashi,
  • Takahashi Kazuhisa

DOI
https://doi.org/10.1186/1746-1596-7-153
Journal volume & issue
Vol. 7, no. 1
p. 153

Abstract

Read online

Abstract In the present case of postoperative lumbar spinal stenosis after non-instrumented intertransverse fusion with granules of hydroxyapatite (HA), bone union was not completed and the patient felt the recurrence of his symptoms within two years. We performed re-decompression with fusion, and in hematoxylin and eosin staining of HA granulation harvested during revision surgery, fibrous tissue with hyaline degeneration surrounded the cavity where the HA had existed. Multinuclear giant cells and lymphocytes infiltrated some parts of the marginal layer of the cavity, and no obvious bony bridge had regenerated from autologous bone. No tartrate-resistant acid phosphate (TRAP) -positive osteoclasts could be seen in the new bone, suggesting that the activity of osteoclasts in the new bone decreased during the seven years after the primary surgery. Virtual slides The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3483360258050263

Keywords