PLoS ONE (Jan 2022)

The analgesic efficacy of pericapsular nerve group block in patients with intertrochanteric femur fracture: A randomized controlled trial.

  • Mingjian Kong,
  • Yan Tang,
  • Fei Tong,
  • Hui Guo,
  • Xin Lei Zhang,
  • Lei Zhou,
  • Hua Ni,
  • Bin Wang,
  • Yunqing Liu,
  • Jindong Liu

DOI
https://doi.org/10.1371/journal.pone.0275793
Journal volume & issue
Vol. 17, no. 10
p. e0275793

Abstract

Read online

BackgroundThe aim of this study is to evaluate analgesic efficacy of pericapsular nerve group (PENG) block in patients with intertrochanteric femur fracture (IFF).MethodsThis double-blinded randomized controlled trial in patients with IFF scheduled for proximal femoral nail antirotation (PFNA) between December 2020 and November 2021. The primary outcome was VAS scores during exercising at 6 h after surgery; secondary outcomes were pain during exercising and rest, intraoperative dose of remifentanil, cumulative dose of postoperative fentanyl, postoperative analgesia satisfaction scores, and ratio of quadriceps weakness.ResultsA total of 50 patients were randomly divided into PENG block group (n = 25) or fascia iliaca compartment block (FICB) group (n = 25). Exercising VAS scores at 6 h after surgery were significantly lower in PENG block group than that in FICB group (2 (2, 4) vs. 6 (4, 7), P ConclusionsCompared to FICB, ultrasound-guided PENG block may provide better postoperative pain relief in patients with IFF, with less pronounced quadriceps weakness.