Journal of Krishna Institute of Medical Sciences University (Jan 2013)
An Epidemiological Study of Cases of Urothelial Carcinoma of Urinary Bladder in a Tertiary Care Centre
Abstract
Background: Urinary bladder cancer is the fourth most common malignancy in Western world. It is a heterogeneous disease with variable natural history. There is paucity of data in our country. Aims and Objectives: The present study aims to assess the risk factors contributing to urothelial carcinoma of bladder in the southern region of West Bengal and histopathological grading (WHO/ISUP). Materials and Methods: It was a retrospective study by multivariate analysis of case record proforma(CRP), agreed upon by a team of experts from the departments of Urosurgery and Pathology,CNMC&H, Kolkata from December, 2007 to November, 2009. Total 88 subjects who had at-tended in the department of urosurgery and al-ready been diagnosed either by cystoscopic bi-opsy or Transurethral Resection of Bladder Tumour (TURBT), were enrolled. Results: There was male preponderance (86.4 % male vs 13.6% female); the age range being 30-81 years(median 65). Hindus (81.8 %) were affected more compared to Muslims (18.2 %). Blood group analysis showed highest incidence in B group (41%) followed by O (32%). Tobacco smoking (75% cases) revealed a strong relationship with bladder cancer and that was quantity and duration dependant. Less water intake(53.4%) and poor socioeconomic status (82%)were significant contributory factors. Analysis of occupational factors gave no epidemiological clue. Histopathological Examination (HPE)revealed low grade urothelial carcinoma (51cases), high grade (24 cases) and papilloma with low malignant potential (13 subjects). Conclusion: Proper epidemiological survey plays a pivotal role in bladder cancer to validate it in the disease control programme.
