Optimisation of Alpha Mangostin Extraction Using Supercritical CO₂ from Garcinia Mangostana

Abstract

This study is designed to optimise the extraction of a mangostin using supercritical carbon dioxide. The extraction parameters were optimised by Box Behnken Design (BBD) with 17-run experiments. The maximum yield of a mangostin is 58.7 wt% under optimum conditions as follows: extraction pressure of 20.01 MPa, thetemperature of 46.25 °C and percentage of co-solvent at 2.9 % of ethanol. To date, this is the first reportdepicting the optimisation of a mangostin from the pericarp of Garcinia Mangostana Linn using supercriticalcarbon dioxide.