CRISPR in 3D: Innovations in Disease Modelling and Personalized Medicine

Abstract

The CRISPR-Cas system of genetic engineering has had a significant impact on science and society since its advent in 2013. CRISPR integration with 3D culture systems such as organ-on-a-chips, as well as fast emerging commercial technologies, has encouraged translation of more complex pathophysiological modelling and personalized medicine.[Figure: see text]

Keywords

• 3D-Culture
• Biotechnology
• CRISPR
• Disease Modelling
• Gene Editing
• Genetic Engineering