Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

Sha-Sha Guo; Sha-Sha Guo; Zhen-Guo Wang; Zhen-Guo Wang

doi:10.3389/fphar.2022.1042745

Frontiers in Pharmacology (Oct 2022)

Salvianolic acid B from Salvia miltiorrhiza bunge: A potential antitumor agent

Sha-Sha Guo,
Sha-Sha Guo,
Zhen-Guo Wang,
Zhen-Guo Wang

Affiliations

Sha-Sha Guo: Key Laboratory of Theory of TCM, Ministry of Education of China, Shandong University of Traditional Chinese Medicine, Jinan, China
Sha-Sha Guo: Institute of Traditional Chinese Medicine Literature and Culture, Shandong University of Traditional Chinese Medicine, Jinan, China
Zhen-Guo Wang: Key Laboratory of Theory of TCM, Ministry of Education of China, Shandong University of Traditional Chinese Medicine, Jinan, China
Zhen-Guo Wang: Institute of Traditional Chinese Medicine Literature and Culture, Shandong University of Traditional Chinese Medicine, Jinan, China

DOI: https://doi.org/10.3389/fphar.2022.1042745
Journal volume & issue: Vol. 13

Abstract

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Salvia miltiorrhiza Bunge (Lamiaceae) is a perennial herb widely found in China since ancient times with a high economic and medicinal value. Salvianolic acid B (Sal-B) is an important natural product derived from Salvia miltiorrhiza and this review summarizes the anticancer activity of Sal-B. Sal-B inhibits tumor growth and metastasis by targeting multiple cell signaling pathways. This review aims to review experimental studies to describe the possible anticancer mechanisms of Sal-B and confirm its potential as a therapeutic drug.

Published in Frontiers in Pharmacology

ISSN: 1663-9812 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://journal.frontiersin.org/journals/pharmacology

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Abstract

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