Enantioselective evaluation of the chiral fungicide mandipropamid: Dissipation, distribution and potential dietary intake risk in tomato, cucumber, Chinese cabbage and cowpea

Abstract

A chiral analytical method was developed and validated for the determination of mandipropamid enantiomers in tomato, cucumber, Chinese cabbage and cowpea. The linearity (R2 > 0.99), accuracy (recovery: 73.8–106%) and precision (relative standard deviation: 0.5). For cucumber and cowpea, the dissipation of the R-enantiomer was preferential (enantiomeric fractions < 0.5). According to the risk quotient data (<< 100%), the residues of mandipropamid in four vegetables were safe for Chinese consumers. This study could provide useful information for the dissipation fate and residue distribution of mandipropamid in vegetables at the enantiomer level and offer some guidance for the dietary intake risk evaluation of mandipropamid in vegetables.

Keywords

• Mandipropamid
• Dissipation
• Residue
• Enantioselectivity
• Dietary intake risk