PLoS ONE (Jan 2021)

Impact of chronic kidney disease on the short- and long-term outcomes of laparoscopic gastrectomy for gastric cancer patients.

  • Katsunobu Sakurai,
  • Naoshi Kubo,
  • Yutaka Tamamori,
  • Naoki Aomatsu,
  • Takafumi Nishii,
  • Akiko Tachimori,
  • Kiyoshi Maeda

DOI
https://doi.org/10.1371/journal.pone.0250997
Journal volume & issue
Vol. 16, no. 4
p. e0250997

Abstract

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BackgroundsThis study was undertaken to investigate the impact of coexisting chronic kidney disease (CKD) on short- and long-term outcomes of laparoscopic gastrectomy in patients with gastric cancer (GC).MethodsWe reviewed the data of 798 patients treated for GC by laparoscopic gastrectomy. All procedures took place between January 2010 and December 2017. Patients were divided into three groups according to their estimated glomerular filtration rate (eGFR): severe CKD group, 44 patients with eGFR ResultsBased on multivariate analysis, severe CKD (eGFR ConclusionsAn eGFR value less than 45 mL/min/1.73 m2 is a useful factor for predicting both anastomotic leak and 5-year OS in GC patients undergoing laparoscopic gastrectomy. Clinical care to improve eGFR should be reinforced before and after gastrectomy for GC patients with severe CKD.