Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) values of optic nerve head in Papilledema

Abstract

Abstract Background Papilledema is optic disc pathology characterized by swelling of the optic disc occurring secondary to elevated intracranial pressure (ICP), and it was proposed that elevated ICP is transferred along the subarachnoid space to the optic nerve (ON) leading to metabolic process interruptions and MRI changes within ON head. This study aimed to rule out if DWI and ADC map can be used as a diagnostic tool for detection of papilledema and if ADC values can be helpful in papilledema grading. Result ADC value was significantly lower in papilledema cases group (A) in comparison with control group (B). Conclusion Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) map can be utilized as a diagnostic tool for diagnosis of papilledema, and ADC values can be helpful in diagnosis of papilledema grade.

Keywords

• Diffusion-weighted imaging (DWI)
• Optic nerve (ON)
• Apparent diffusion coefficient (ADC)