Hydroalcoholic extract of Haematoxylum brasiletto protects Caenorhabditis elegans from cadmium-induced toxicity

Abstract

Highlights Most secondary metabolites tentatively identified in H. brasiletto are homoisoflavones. Hidroalcoholic extract of H. brasiletto protects C. elegans from Cd toxicity The extract diminished Cd-induced damage to reproduction, growth, and locomotion. Cd-induced oxidative stress and translocation of DAF-16 are blocked by the extract.

Keywords

• Nematode
• Oxidative stress
• Fabaceae
• Daf-16
• Biodiversity