Granular cell tumor in abdominal wall: case report

Abstract

Introduction: Granular cell tumor (GCT), formerly known as granular cell myoblastoma, is an uncommon soft tissue neoplasm that may be of neural or neuroectodermal origin. For a long time, this neoplastic lesion was considered to be of striated muscle origin. This type of tumor can be found anywhere in the body, but rarely in the abdominal wall. In this study, we report a granular cell tumor in abdominal wall. Case presentation: We report a 54-year-old woman with relatively painful and rigid abdominal wall lesion in the suprapubic area from 20 days before admission. Ultrasound and CT scan were performed and the patient underwent abdominal wall mass excision surgery in the suprapubic region. Surgical resection was performed extensively with the removal of adjacent muscles and fascia. Preoperative histopathologic diagnosis is important because one of the therapeutic targets of GCT is extensive excision to obtain tumor-free margins, as in the case of margin involvement, the chance of recurrence is high. Then, the sample was sent to the pathology department for further examination, and immunohistochemistry study with CK, chromogranin, S100, and CD68 markers was done for final diagnosis. Since abdominal wall GCT is a very rare clinically and radiologically finding and can mimic malignant symptoms, it is important to correctly diagnose it. Conclusion:Due to the numerous reported cases of this lesion in women and the possibility of more encountering of gynecologists with this case, the need for accurate knowledge of this lesion in the gynecological surgery group is of greater importance to prevent the consequences of improper treatment.

Keywords

• abdominal wall
• granular cell tumor (gct)
• histopathologic diagnosis