Tropical Medicine and Infectious Disease (Jul 2021)

Implementation of an Effective Decentralised Programme for Detection, Treatment and Prevention of Tuberculosis in Children

  • John Paul Dongo,
  • Stephen M. Graham,
  • Joseph Nsonga,
  • Fred Wabwire-Mangen,
  • Elizabeth Maleche-Obimbo,
  • Ezekiel Mupere,
  • Rodrigo Nyinoburyo,
  • Jane Nakawesi,
  • Gerald Sentongo,
  • Pauline Amuge,
  • Anne Detjen,
  • Frank Mugabe,
  • Stavia Turyahabwe,
  • Moorine P. Sekadde,
  • Stella Zawedde-Muyanja

DOI
https://doi.org/10.3390/tropicalmed6030131
Journal volume & issue
Vol. 6, no. 3
p. 131

Abstract

Read online

Childhood tuberculosis (TB) is consistently under-detected in most high-burden countries, including Uganda, especially in young children at high risk for severe disease and mortality. TB preventive treatment (TPT) for high-risk child contacts is also poorly implemented. The centralised concentration of services for child TB at the referral level is a major challenge in the prevention, detection and treatment of TB in children. In 2015, the DETECT Child TB Project was implemented in two districts of Uganda and involved decentralisation of healthcare services for child TB from tertiary to primary healthcare facilities, along with establishing linkages to support community-based household contact screening and management. The intervention resulted in improved case finding of child and adult TB cases, improved treatment outcomes for child TB and high uptake and completion of TPT for eligible child contacts. A detailed description of the development and implementation of this project is provided, along with findings from an external evaluation. The ongoing mentorship and practical support for health workers to deliver optimal services in this context were critical to complement the use of training and training tools. A summary of the project’s outcomes is provided along with the key challenges identified and the lessons learnt.

Keywords