Advances in diagnostics and management of gestational trophoblastic disease

Abstract

Gestational trophoblastic disease (GTD) is a heterogeneous group of rare tumours characterised by abnormal proliferation of trophoblastic tissue. It consists of benign or premalignant conditions, such as complete and partial molar pregnancy and variants of malignant diseases. The malignant tumours specifically are commonly referred to as gestational trophoblastic neoplasia (GTN). They consist of invasive mole, choriocarcinoma, placental-site trophoblastic tumour (PSTT) and epithelioid trophoblastic tumour (ETT).

Keywords

• gestational trophoblastic disease
• hydatidiform mole
• molar pregnancy
• gestational trophoblastic neoplasia
• human chorionic gonadotropin
• invasive mole
• choriocarcinoma