EFEITO DO PROBIÓTICO APÓS TOXICIDADE HEPÁTICA DO DICROMATO DE POTÁSSIO EM RATOS

Abstract

This work aims to evaluate the alterations, depending on the dose of potassium dichromate (0, 12, 24 and 36 mg.kg-¹), in liver tissue after supplementation with probiotic at dosages 0 or 0.2% in 80 male rats. Oral ingestion done for 90 days of increasing amounts of potassium dichromate produced clinical signs of toxicity compared to histopathological analysis (p˂0.05), and seric enzymatic activities (p˂0.05), markers of hepatic function. The inclusion of probiotics to the diet mitigated the effects on the studied parameters

Keywords

• chromium vi
• intoxication
• seric enzymatic activity
• histopathology
• rats