Nature Communications (Jul 2016)
Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus
- Ruijun Zhang,
- David R. Martinez,
- Quang N. Nguyen,
- Justin Pollara,
- Trina Arifin,
- Christina Stolarchuk,
- Andrew Foulger,
- Josh D. Amos,
- Robert Parks,
- Jonathon E. Himes,
- Minyue Wang,
- Regina W. Edwards,
- Ashley M. Trama,
- Nathan Vandergrift,
- Lisa Colvin,
- Ken Dewar,
- Nikoleta Juretic,
- Jessica Wasserscheid,
- Guido Ferrari,
- Hua-Xin Liao,
- Sallie R. Permar
Affiliations
- Ruijun Zhang
- Duke Human Vaccine Institute, Duke University School of Medicine
- David R. Martinez
- Duke Human Vaccine Institute, Duke University School of Medicine
- Quang N. Nguyen
- Duke Human Vaccine Institute, Duke University School of Medicine
- Justin Pollara
- Duke Human Vaccine Institute, Duke University School of Medicine
- Trina Arifin
- Duke Human Vaccine Institute, Duke University School of Medicine
- Christina Stolarchuk
- Duke Human Vaccine Institute, Duke University School of Medicine
- Andrew Foulger
- Duke Human Vaccine Institute, Duke University School of Medicine
- Josh D. Amos
- Duke Human Vaccine Institute, Duke University School of Medicine
- Robert Parks
- Duke Human Vaccine Institute, Duke University School of Medicine
- Jonathon E. Himes
- Duke Human Vaccine Institute, Duke University School of Medicine
- Minyue Wang
- Duke Human Vaccine Institute, Duke University School of Medicine
- Regina W. Edwards
- Duke Human Vaccine Institute, Duke University School of Medicine
- Ashley M. Trama
- Duke Human Vaccine Institute, Duke University School of Medicine
- Nathan Vandergrift
- Duke Human Vaccine Institute, Duke University School of Medicine
- Lisa Colvin
- Duke Human Vaccine Institute, Duke University School of Medicine
- Ken Dewar
- Research Institute of the McGill University Health Centre, McGill University and Génome Québec Innovation Centre
- Nikoleta Juretic
- Research Institute of the McGill University Health Centre, McGill University and Génome Québec Innovation Centre
- Jessica Wasserscheid
- Research Institute of the McGill University Health Centre, McGill University and Génome Québec Innovation Centre
- Guido Ferrari
- Duke Human Vaccine Institute, Duke University School of Medicine
- Hua-Xin Liao
- Duke Human Vaccine Institute, Duke University School of Medicine
- Sallie R. Permar
- Duke Human Vaccine Institute, Duke University School of Medicine
- DOI
- https://doi.org/10.1038/ncomms12131
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 11
Abstract
Infection of African green monkeys with simian immunodeficiency virus is a potential model for HIV vaccine development. Here, Zhang et al. catalogue the immunoglobulin loci present in the genome of these animals, and experimentally study their B-cell response to the viral envelope protein.
