Rational use of antibiotics in stationary health care institution: Case study

Abstract

Between 25% and 50% of hospitalized patients receive antibiotics. Some studies estimate that 25-68% of hospital antibiotic prescribing is suboptimal. The aim of this study was to analyse antibiotic use in Medical Center 'Bežanijska Kosa'. For the period 2008-2012, yearly data on antibiotic use in inpatients were obtained from the database of the hospital pharmacy and expressed as DDD per 100 bed-days. The total antibiotic use varied during the study period from 62,3 to 65,6 DDD per 100 bed-days. The most frequently used antibiotics were cephalosporins, followed by fluoroquinolones, penicillins and aminoglycosides. Ceftriaxone was the most frequently prescribed antibiotic. The findings emphasize the need for effective measures to reduce widespread antibiotic misusage in hospitals.

Keywords

• antibiotic
• use
• hospital