Saudi Pharmaceutical Journal (Jul 2024)

Recognition on pharmacodynamic ingredients of natural products

  • Tao Wang,
  • Zhong-Yu Fu,
  • Yan-Juan Li,
  • Lei Zi,
  • Cheng-Zhu Song,
  • Yu-Xuan Tao,
  • Mei Zhang,
  • Wen Gu,
  • Jie Yu,
  • Xing-Xin Yang

Journal volume & issue
Vol. 32, no. 7
p. 102124

Abstract

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Natural products (NPs) play an irreplaceable role in the intervention of various diseases and have been considered a critical source of drug development. Many new pharmacodynamic compounds with potential clinical applications have recently been derived from NPs. These compounds range from small molecules to polysaccharides, polypeptides, proteins, self-assembled nanoparticles, and extracellular vesicles. This review summarizes various active substances found in NPs. The investigation of active substances in NPs can potentiate new drug development and promote the in-depth comprehension of the mechanism of action of NPs that can be beneficial in the prevention and treatment of human diseases.

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