Case Report: Sudden death caused by methylene chloride poisoning

Ruikai Shang; Ruikai Shang; Qiaoxin Tian; Qiaoxin Tian; Yuru Liu; Hongyu Liu; Xiangxing Zhang; Xiangxing Zhang; Mengdi Shi; Mengdi Shi; Xiangdong Jian; Xiangdong Jian; Qilu Li

doi:10.3389/fphar.2024.1471744

Frontiers in Pharmacology (Nov 2024)

Case Report: Sudden death caused by methylene chloride poisoning

Ruikai Shang,
Ruikai Shang,
Qiaoxin Tian,
Qiaoxin Tian,
Yuru Liu,
Hongyu Liu,
Xiangxing Zhang,
Xiangxing Zhang,
Mengdi Shi,
Mengdi Shi,
Xiangdong Jian,
Xiangdong Jian,
Qilu Li

Affiliations

Ruikai Shang: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Ruikai Shang: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Qiaoxin Tian: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Qiaoxin Tian: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Yuru Liu: School of Nursing and Rehabilitation, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Hongyu Liu: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Xiangxing Zhang: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Xiangxing Zhang: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Mengdi Shi: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Mengdi Shi: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Xiangdong Jian: Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Xiangdong Jian: Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China
Qilu Li: Department of Pharmacy, the Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China

DOI: https://doi.org/10.3389/fphar.2024.1471744
Journal volume & issue: Vol. 15

Abstract

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Dichloromethane is widely used as an organic solvent in aerospace, electronics, and medicine. Cases of poisoning caused by this substance are rare. Recently, we successfully treated a patient with an acute dichloromethane poisoning. During the production process, owing to pipeline leakage and lack of personal protection, the patient was poisoned by dichloromethane inhalation, fell from a height, and experienced a sudden cardiac arrest. After successful cardiopulmonary resuscitation, the patient was transferred to a local hospital for diagnosis and treatment and then to our hospital. After two visits to our hospital for systematic diagnosis and active treatment with fluid infusion, anti-infection therapy, glucocorticoids, ventilator-assisted respiration, chest strap fixation, and nutritional support, the patient achieved clinical recovery.

Published in Frontiers in Pharmacology

ISSN: 1663-9812 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://journal.frontiersin.org/journals/pharmacology

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