In Silico and in Vitro Studies of Fluorinated Chroman-2-Carboxilic Acid Derivatives as an Anti-tubercular Agent

Kapadiya Khushal M.; Jadeja Yashwantsinh S.; Banik Avishek; Khunt Ranjan C.

doi:10.2478/folmed-2018-0034

Folia Medica (Dec 2018)

In Silico and in Vitro Studies of Fluorinated Chroman-2-Carboxilic Acid Derivatives as an Anti-tubercular Agent

Kapadiya Khushal M.,
Jadeja Yashwantsinh S.,
Banik Avishek,
Khunt Ranjan C.

Affiliations

Kapadiya Khushal M.: Department of Chemistry, RK University, Rajkot, Gujarat, India
Jadeja Yashwantsinh S.: Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India
Banik Avishek: Department of Microbiology, RK University, Rajkot, Gujarat, India
Khunt Ranjan C.: Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India

DOI: https://doi.org/10.2478/folmed-2018-0034
Journal volume & issue: Vol. 60, no. 4
pp. 601 – 609

Abstract

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Background: Despite the use of traditional method, Ugi reaction currently is a well-established multicomponent reaction. Chromane motif itself possesses a variety of biological functions. In order to improve its anti-tubercular activity, it is necessary to modify it accordingly.

Published in Folia Medica

ISSN: 0204-8043 (Print); 1314-2143 (Online)
Publisher: Pensoft Publishers
Country of publisher: Bulgaria
LCC subjects: Medicine
Website: https://foliamedica.bg

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Abstract

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