Plasmapheresis for Refractory Pruritus due to Drug-Induced Cholestasis

Abstract

Pruritus can be a distressing symptom seen in various cholestatic disorders. It is treated with medications like bile acid sequestrants. Drug-induced cholestasis usually resolves with withdrawal of the causative medication. We describe a case of refractory pruritus due to drug-induced cholestasis, not improved with withdrawal of the drug, managed effectively with multiple sessions of plasmapheresis.

Keywords

• Refractory
• Plasmapheresis
• Cholestasis
• Pruritus
• Drug-induced cholestasis