Chemosensors (Aug 2023)

Advances in the Application of Nano-Enzymes in the Electrochemical Detection of Reactive Oxygen Species: A Review

  • Rongwei Gao,
  • Shujuan Bao

DOI
https://doi.org/10.3390/chemosensors11080440
Journal volume & issue
Vol. 11, no. 8
p. 440

Abstract

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Reactive oxygen species (ROS) play an important role in maintaining human health and are recognized as indicators of oxidative stress linked to various conditions such as neurodegenerative and cardiovascular diseases, as well as cancer. Consequently, detecting ROS levels in biological systems is crucial for biomedical and analytical research. Electrochemical approaches offer promising opportunities for ROS determination due to their exceptional sensitivity, speed, and simplicity of equipment. This review covers studies using advanced electrochemical nanozyme sensors for detecting ROS in biological samples that were published over the last ten years, from 2013 to 2023. Emphasis is placed on the sensor materials and different types of modifiers employed for selective ROS detection. Furthermore, a comprehensive analysis of the sensors’ selectivity was performed.

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