Human Vaccines & Immunotherapeutics (Dec 2023)

Factors associated with the decision to receive bivalent COVID-19 booster vaccination among health care personnel

  • Nicholas M. Mohr,
  • Ian D. Plumb,
  • Eliezer Santos León,
  • Karisa K. Harland,
  • Anusha Krishnadasan,
  • Utsav Nandi,
  • Karin F. Hoth,
  • Howard A. Smithline,
  • David A. Talan

DOI
https://doi.org/10.1080/21645515.2023.2284471
Journal volume & issue
Vol. 19, no. 3

Abstract

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ABSTRACTCOVID-19 vaccination is effective at reducing SARS-CoV-2 complications, but uptake has been low. Our objective in this study was to compare the importance of factors reported to influence the decision to receive a bivalent COVID-19 booster vaccine among health care personnel (HCP) tested for SARS-CoV-2 between October 2022 and April 2023 in a 20-hospital vaccine effectiveness study in the United States (n = 1656). Compared with those who had not received the booster, the factors most likely to be reported to be important were concerns about contracting COVID-19 (84.0% of those who had received the bivalent booster vs. 47.5% of those who had not, difference 36.6% points (PP), 95% confidence interval [CI] 32.1 to 41.1%), spreading infection to family members (89.2% vs. 62.8%, difference 26.3 PP, 95% CI 22.3 to 30.4%), and spreading infection to colleagues at work (85.5% vs. 59.4%, difference 26.1 PP, 95% CI 21.7 to 30.5%). HCP who had received the booster more frequently cited the primary literature (61.7% vs. 31.8%, difference 29.9 PP, 95% CI 24.6 to 35.2%) and employer recommendations (48.3% vs. 29.8%, difference 18.5 PP, 95% CI 13.2 to 23.9%) as influencing their decision. This analysis provides insight into factors for targeting future vaccine messaging.

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