The maternal reduced uteroplacental perfusion model of preeclampsia induces sexually dimorphic metabolic responses in rat offspring

Mohammadmehdi Hassanzadeh-Taheri; Mahtab Mohammadifard; Zahra Erfanian; Mehran Hosseini

doi:10.1186/s13293-022-00458-8

Biology of Sex Differences (Sep 2022)

The maternal reduced uteroplacental perfusion model of preeclampsia induces sexually dimorphic metabolic responses in rat offspring

Mohammadmehdi Hassanzadeh-Taheri,
Mahtab Mohammadifard,
Zahra Erfanian,
Mehran Hosseini

Affiliations

Mohammadmehdi Hassanzadeh-Taheri: Cellular and Molecular Research Center, Department of Anatomical Sciences, Birjand University of Medical Sciences
Mahtab Mohammadifard: Department of Pathology, Faculty of Medicine, Birjand University of Medical Sciences
Zahra Erfanian: Faculty of Medicine, Birjand University of Medical Sciences
Mehran Hosseini: Cellular and Molecular Research Center, Department of Anatomical Sciences, Birjand University of Medical Sciences

DOI: https://doi.org/10.1186/s13293-022-00458-8
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 12

Abstract

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Highlights Pancreatic insulin production was reduced in adult male offspring born to reduced uteroplacental perfusion (RUPP) rats. Offspring born to RUPP dams exhibited sex-specific alterations in insulin, ghrelin and glucagon changes.

Published in Biology of Sex Differences

ISSN: 2042-6410 (Online)
Publisher: BMC
Country of publisher: United Kingdom
LCC subjects: Medicine; Science: Physiology
Website: http://bsd.biomedcentral.com

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Abstract

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