PLoS Biology (Jan 2012)

Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies.

  • Daniel Russel,
  • Keren Lasker,
  • Ben Webb,
  • Javier Velázquez-Muriel,
  • Elina Tjioe,
  • Dina Schneidman-Duhovny,
  • Bret Peterson,
  • Andrej Sali

DOI
https://doi.org/10.1371/journal.pbio.1001244
Journal volume & issue
Vol. 10, no. 1
p. e1001244

Abstract

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A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models.