Intravitreal moxifloxacin in the management of Ochrobactrum intermedium endophthalmitis due to metallic intraocular foreign body

Abstract

David J Jacobs,1,2 Thomas J Grube,3 Harry W Flynn Jr,4 Craig M Greven,5 Avinash Pathengay,6 Darlene Miller,4 Robert F Sanke,1,2 Joseph Thorman7 1Trinity Regional Eyecare, Minot, ND, USA; 2School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND, USA; 3Grube Retina Clinic, Mandan, ND, USA; 4Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA; 5Department of Ophthalmology, Wake Forest University Eye Center, Winston-Salem, NC, USA; 6LV Prasad Eye Institute, Hyderabad, India; 7Rolla Eye Clinic, ND, USA Abstract: A healthy 34-year-old man presented with Ochrobactrum intermedium endophthalmitis due to a metallic intraocular foreign body. After vitrectomy, lensectomy, removal of the metallic intraocular foreign body, intravitreal vancomycin and ceftazidime, and systemic ciprofloxacin, intraocular inflammation worsened. Repeat vitreous culture confirmed persistent endophthalmitis due to multidrug-resistant O. intermedium. The endophthalmitis successfully resolved after the administration of intravitreal moxifloxacin. Keywords: moxifloxacin, Ochrobactrum intermedium, endophthalmitis, intraocular foreign body