Center for Communicable Disease Dynamics, Department of Epidemiology, and Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, United States; Department of Pathology, Brigham and Women’s Hospital, Boston, United States
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States; Woodrow Wilson School, Princeton University, Princeton, United States
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States; Woodrow Wilson School, Princeton University, Princeton, United States; Fogarty International Center, National Institutes of Health, Bethesda, United States
SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise.