Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children

Melanie R. Neeland; Samantha Bannister; Vanessa Clifford; Kate Dohle; Kim Mulholland; Philip Sutton; Nigel Curtis; Andrew C. Steer; David P. Burgner; Nigel W. Crawford; Shidan Tosif; Richard Saffery

doi:10.1038/s41467-021-21414-x

Nature Communications (Feb 2021)

Innate cell profiles during the acute and convalescent phase of SARS-CoV-2 infection in children

Melanie R. Neeland,
Samantha Bannister,
Vanessa Clifford,
Kate Dohle,
Kim Mulholland,
Philip Sutton,
Nigel Curtis,
Andrew C. Steer,
David P. Burgner,
Nigel W. Crawford,
Shidan Tosif,
Richard Saffery

Affiliations

Melanie R. Neeland: Infection and Immunity Theme, Murdoch Children’s Research Institute
Samantha Bannister: Infection and Immunity Theme, Murdoch Children’s Research Institute
Vanessa Clifford: Infection and Immunity Theme, Murdoch Children’s Research Institute
Kate Dohle: Department of Paediatrics, The University of Melbourne
Kim Mulholland: Infection and Immunity Theme, Murdoch Children’s Research Institute
Philip Sutton: Infection and Immunity Theme, Murdoch Children’s Research Institute
Nigel Curtis: Infection and Immunity Theme, Murdoch Children’s Research Institute
Andrew C. Steer: Infection and Immunity Theme, Murdoch Children’s Research Institute
David P. Burgner: Infection and Immunity Theme, Murdoch Children’s Research Institute
Nigel W. Crawford: Infection and Immunity Theme, Murdoch Children’s Research Institute
Shidan Tosif: Infection and Immunity Theme, Murdoch Children’s Research Institute
Richard Saffery: Infection and Immunity Theme, Murdoch Children’s Research Institute

DOI: https://doi.org/10.1038/s41467-021-21414-x
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 5

Abstract

Read online

Childhood infection with SARS CoV2 is associated with a milder course of infection but the immunopathogenesis of this remains unclear. Here the authors explore immunological differences in the innate immune system during acute and convalescent SARS CoV2 infection in the young.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal