BOTULINUM IN MODERN UROLOGY

Abstract

The advent of botulinum toxin (BT) in healthcare has revolutionized the treatment of several diseases and the aesthetic medicine. Botulinum toxin is a powerful neurotoxin with a paralytic/muscle relaxant effect. The most potent substance has been successfully used for the treatment of pathological conditions that can not be effectively managed and provide a stable effect with other known methods. Many disorders of the lower urinary tract function are associated with muscle hypertonia or spasms and can be treated with accurate infiltration of BT in the concerned area. Treatment of idiopathic overactive bladder using BT is also effective and safe. Efficacy and safety of BT administration for neurogenic and idiopathic DO were investigated and confirmed in large multicenter trials.

Keywords

• botulinum toxin type a
• ndo
• idiopathic detrusor overactivity
• combined urodynamic study
• overactive bladder
• urinary incontinence