Cailiao Baohu (Feb 2023)

Study on the Antibacterial Performance of Ti-ZnO Nanocomposite Coatings on Implant Surface

  • JI Zhen-yu, MA Xun, LIU Ping, WANG Jing-jing, MA Feng-cang, ZHANG Ke, CHEN Xiao-hong, LIU Jian-nan, LI Wei

DOI
https://doi.org/10.16577/j.issn.1001-1560.2023.0028
Journal volume & issue
Vol. 56, no. 2
pp. 1 – 8

Abstract

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In order to aovid peri-implantitis，Ti-ZnO nanocomposite coatings were prepared on the surface of pure Ti slices by reactive magnetron sputtering.The effects of nano-ZnO content on the microstructure and antibacterial performance of the coatings were studied by means of changing the splicing ratio of Ti target and ZnO target.The microstructure，roughness and wettability of the samples were characterized and measured by scanning electron microscopy (SEM)，X-ray diffraction (XRD)，atomic force microscopy (AFM) and JC2000C1 interfacial tension tester.In addition，the release of Zn ions from the coatings was measured by inductively coupled plasma-mass spectrometry (ICP-MS)，the cytotoxicity of the coatings was tested by CCK-8 method，and the antibacterial performance of the coatings was evaluated by plate colony counting method.Results showed that when the ratio of Ti target to ZnO target was 95 ∶5，the nano-ZnO content in Ti-ZnO coating was the highest，the roughness and contact angle with liquid phase of the coating reached the maximum values of 0.547 nm and 101.25° respectively，the coating had no cytotoxicity and met the standards for biosafety materials，and the antibacterial performance of the coating was the best with an antibacterial rate up to 91.05%.

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