Differential constituents in roots, stems and leaves of Newbouldia laevis Thunb. screened by LC/ESI-Q-TOF-MS

Affo Dermane; Kafui Kpegba; Kodjo Eloh; Dorcas Osei-Safo; Richard K. Amewu; Pierluigi Caboni

Results in Chemistry (Jan 2020)

Differential constituents in roots, stems and leaves of Newbouldia laevis Thunb. screened by LC/ESI-Q-TOF-MS

Affo Dermane,
Kafui Kpegba,
Kodjo Eloh,
Dorcas Osei-Safo,
Richard K. Amewu,
Pierluigi Caboni

Affiliations

Affo Dermane: Department of Pharmaceutical Sciences, University of Lomé, 01 BP 1515 Lomé 01, Lomé, Togo
Kafui Kpegba: Laboratoire de Chimie Organique et des Substances Naturelles (Lab COSNat), Département de Chimie, Faculté Des Sciences, Université de Lomé, 01 BP 1515 Lomé 01, Lomé, Togo
Kodjo Eloh: Department of Life and Environmental Sciences, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy; Corresponding author at: Via Ospedale 72, 09124 Cagliari, Italy.
Dorcas Osei-Safo: Chemistry Department, University of Ghana, P.O. Box LG 56, Legon, Ghana
Richard K. Amewu: Chemistry Department, University of Ghana, P.O. Box LG 56, Legon, Ghana
Pierluigi Caboni: Department of Life and Environmental Sciences, University of Cagliari, Via Ospedale 72, 09124 Cagliari, Italy

Journal volume & issue: Vol. 2
p. 100052

Abstract

Read online

Newbouldia laevis (P. Beauv.) Seem. or “Boundary Tree” is a medium sized angiosperm in the Bignoniaceae family. It is native to tropical Africa, especially used in West Africa to mark property boundaries in rural areas. Despite its intensive use in folk medicine, the plant chemical composition is under investigated. The study is aimed at identifying the chemical constituents of N. laevis crude plant extracts by high-performance liquid chromatography (HPLC) on line with an untargeted high-resolution mass spectrometry. The used HPLC method showed to be suitable for the determination of withasomnine, newbouldine, and lapachol derivatives together with other known bioactive compounds like phytosterols and triterpenoids. The importance of these chemical constituents is discussed with respect to the role of N. laevis in West African ethnomedicine.

Published in Results in Chemistry

ISSN: 2211-7156 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Chemistry
Website: https://www.journals.elsevier.com/results-in-chemistry/

About the journal

Abstract

Keywords