Clinical and laboratory features of atypical mycobacteriosis in HIV-patients

Abstract

In recent years, in Russia we found growing number of mycobacteriosis caused by nontuberculous mycobacteria in patients with HIV infection. The aim of this study was to evaluate dynamics of the detection of MAC-infection in HIVinfected patients in St. Petersburg and conduct the clinical and laboratory characteristics of them. To accomplish the task, carried out a retrospective analysis of 94 patients with HIV and mycobacteriosis treated in City TB Hospital №2 of St. Petersburg in 2004–2015 years. Mycobacteriosis cases were recorded in patients with advanced HIV disease who were not receiving HAART. High level of social adaptation of patients with mycobacteriosis (HIV infection mainly through sexual contact, low frequency of the active drug using, high level of employment, low level of imprisonment history). The clinical features was symptoms of intoxication, diarrheal syndrome. X-ray examination of chest demonstrated an increase in mediastinal lymph nodes at the scarcity of dissemination in lung tissue. In the laboratory attracted attention the presence of severe anemia and increase markers of cholestasis (GGT and alkaline phosphatase).

Keywords

• atypical mycobacterium infections
• mycobacteriosis
• aids
• hiv-infection
• mac-infection