Fungal Biology and Biotechnology (Jul 2024)

A review on the cultivation, bioactive compounds, health-promoting factors and clinical trials of medicinal mushrooms Taiwanofungus camphoratus, Inonotus obliquus and Tropicoporus linteus

  • Phoebe Yon Ern Tee,
  • Thiiben Krishnan,
  • Xin Tian Cheong,
  • Snechaa A. P. Maniam,
  • Chung Yeng Looi,
  • Yin Yin Ooi,
  • Caroline Lin Lin Chua,
  • Shin-Yee Fung,
  • Adeline Yoke Yin Chia

DOI
https://doi.org/10.1186/s40694-024-00176-3
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 39

Abstract

Read online

Abstract Medicinal mushrooms, such as Taiwanofungus camphoratus, Inonotus obliquus, and Tropicoporus linteus, have been used in traditional medicine for therapeutic purposes and promotion of overall health in China and many East Asian countries for centuries. Modern pharmacological studies have demonstrated the large amounts of bioactive constituents (such as polysaccharides, triterpenoids, and phenolic compounds) available in these medicinal mushrooms and their potential therapeutic properties. Due to the rising demand for the health-promoting medicinal mushrooms, various cultivation methods have been explored to combat over-harvesting of the fungi. Evidence of the robust pharmacological properties, including their anticancer, hypoglycemic, hypolipidemic, antioxidant, and antiviral activities, have been provided in various studies, where the health-benefiting properties of the medicinal fungi have been further proven through numerous clinical trials. In this review, the cultivation methods, available bioactive constituents, therapeutic properties, and potential uses of T. camphoratus, I. obliquus and T. linteus are explored.

Keywords