Application of platelet-rich plasma on androgenic alopecia

Abstract

Platelet-rich plasma (PRP) is rich in growth factors, cytokines and other biological active substances, which can promote cell proliferation, differentiation, matrix synthesis, tissue regeneration and repair, etc. Although its production process is not complicated, there is still no unified production standard in the world. Androgenetic alopecia (AGA) is a common type of hair loss in clinic. PRP has been proved to be an effective and safe treatment for AGA by several experiments and clinical studies in recent years. In addition to simple subscalp injection of PRP, PRP combined with microneedles, drugs, adipose transplantation, low energy laser therapy, non-ablative Er: YAG and other treatments have been derived. This paper summarized and analyzed relevant literatures and experiments in recent years, aiming to review the research progress of PRP in the treatment of AGA in terms of mechanism of action, preparation method and treatment method, and provide more theoretical and practical basis for clinicians.

Keywords

• platelety-rich plasma
• androgenetic alopecia
• injection treatment