Copper-Catalyzed Dimerization/Cyclization of Itaconates

Abstract

A copper-catalyzed domino reaction between itaconate esters and diethyl zinc (or silane) is developed, affording itaconate dimerization products, multi-ester-substituted cyclopentanones, in moderate to high yields.

Keywords

• copper
• catalysis
• domino reaction
• itaconate
• dimerization
• cyclopentanone