The analysis of association of polymorphism of IL-4, IL-10 and TNF cytokine genes with biochemical and immunological indicators in patients with chronic hepatitis C

Abstract

The article presents studies of the genetic profile (IL-4 (C589T), IL-10 (G1082A) and TNF-α (G308A)), clinical and biochemical indices in 100 patients with chronic hepatitis C living in the Odesa region. Possible markers of the severity of disease course and its prognosis were detected.

Keywords

• chronic hepatitis C
• disease progression
• polymorphism of cytokine genes