Research progress of PLGA microspheres in stomatology

Abstract

Compared with other drug loading methods, PLGA drug-loaded microspheres have the advantages of sustained and controlled release ability, biodegradability, drug release stability, and targeted delivery function, which have become a research hotspot in pharmaceutics. With the improvement of the preparation technology and the quality of microspheres, they have been gradually promoted in clinical practice, and have achieved remarkable results in the treatment of tumors, osteoarthritis, diabetes, eye diseases and so on. However, there is still a lack of systematic review on the application of PLGA microspheres in stomatology. This article aims to introduce the clinical application characteristics of PLGA microspheres, and review their application prospect in oral and maxillofacial tumors, temporomandibular joint diseases, periodontitis, caries and alveolar bone defects, so as to provide reference for their application in stomatology.

Keywords

• |plga|microspheres|sustained release|stomatology