Does this HIV-positive patient have progressive multifocal leukoencephalopathy or PML-immune reconstitution inflammatory syndrome?

Abstract

We describe the case of an HIV/AIDS patient with progressive multifocal leukoencephalopathy (PML) associated with immune reconstitution inflammatory syndrome (IRIS) and the diagnostic and management dilemmas in distinguishing between PML and PML-IRIS. This case is relevant to physicians including family physicians who manage immunocompromised patients in their practice.

Keywords

• Acquired immunodeficiency syndrome (Source: MeSH-NLM)
• HIV
• immune reconstitution inflammatory syndrome
• JC virus
• leukoencephalopathy
• progressive multifocal