Nature Communications (Mar 2016)
Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
- Jacqueline M. Lane,
- Irma Vlasac,
- Simon G. Anderson,
- Simon D. Kyle,
- William G. Dixon,
- David A. Bechtold,
- Shubhroz Gill,
- Max A. Little,
- Annemarie Luik,
- Andrew Loudon,
- Richard Emsley,
- Frank A. J. L. Scheer,
- Deborah A. Lawlor,
- Susan Redline,
- David W. Ray,
- Martin K. Rutter,
- Richa Saxena
Affiliations
- Jacqueline M. Lane
- Center for Human Genetic Research Massachusetts General Hospital
- Irma Vlasac
- Center for Human Genetic Research Massachusetts General Hospital
- Simon G. Anderson
- Cardiovascular Research Group, Institute of Cardiovascular Sciences, The University of Manchester
- Simon D. Kyle
- Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute (SCNi), University of Oxford
- William G. Dixon
- Centre for Musculoskeletal Research Institute of Inflammation and Repair, The University of Manchester
- David A. Bechtold
- Faculty of Life Sciences, The University of Manchester
- Shubhroz Gill
- Chemical Biology Program, Broad Institute, Cambridge
- Max A. Little
- Department of Mathematics, Engineering and Applied Science, Aston University
- Annemarie Luik
- Nuffield Department of Clinical Neurosciences, Sleep and Circadian Neuroscience Institute (SCNi), University of Oxford
- Andrew Loudon
- Faculty of Life Sciences, The University of Manchester
- Richard Emsley
- Institute of Population Health, The University of Manchester
- Frank A. J. L. Scheer
- Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital
- Deborah A. Lawlor
- MRC Integrative Epidemiology Unit at the University of Bristol
- Susan Redline
- Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital
- David W. Ray
- Centre for Endocrinology and Diabetes, Institute of Human Development, The University of Manchester
- Martin K. Rutter
- Centre for Endocrinology and Diabetes, Institute of Human Development, The University of Manchester
- Richa Saxena
- Center for Human Genetic Research Massachusetts General Hospital
- DOI
- https://doi.org/10.1038/ncomms10889
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 10
Abstract
Here, Richa Saxena and colleagues perform a genome-wide association study (GWAS) of self-reported morningness/eveningness preference in the UKBiobank cohort, and identify new genetic loci that contribute to a person's chronotype.
