Applied Sciences (Mar 2019)

Modification of Chitosan for the Generation of Functional Derivatives

  • Clément Brasselet,
  • Guillaume Pierre,
  • Pascal Dubessay,
  • Marguerite Dols-Lafargue,
  • Joana Coulon,
  • Julie Maupeu,
  • Amélie Vallet-Courbin,
  • Hélène de Baynast,
  • Thierry Doco,
  • Philippe Michaud,
  • Cédric Delattre

DOI
https://doi.org/10.3390/app9071321
Journal volume & issue
Vol. 9, no. 7
p. 1321

Abstract

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Today, chitosan (CS) is probably considered as a biofunctional polysaccharide with the most notable growth and potential for applications in various fields. The progress in chitin chemistry and the need to replace additives and non-natural polymers with functional natural-based polymers have opened many new opportunities for CS and its derivatives. Thanks to the specific reactive groups of CS and easy chemical modifications, a wide range of physico-chemical and biological properties can be obtained from this ubiquitous polysaccharide that is composed of β-(1,4)-2-acetamido-2-deoxy-d-glucose repeating units. This review is presented to share insights into multiple native/modified CSs and chitooligosaccharides (COS) associated with their functional properties. An overview will be given on bioadhesive applications, antimicrobial activities, adsorption, and chelation in the wine industry, as well as developments in medical fields or biodegradability.

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